35 Results for "

Phytolacca americana L.

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "Phytolacca americana L." in MCE Product Catalog:

53
Silvestrol
Silvestrol
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53 Publications Verification
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Category:  

Agave americana Linn. Natural Products Agavaceae Plants Disease Research Fields Cancer

Target:  

Eukaryotic Initiation Factor (eIF) Apoptosis Autophagy

Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
2
Esculentoside A
Esculentoside A
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2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
Category:  

Triterpenes Terpenoids Phytolacca acinosa Roxb. Plants Disease Research Fields Inflammation/Immunology Phytolaccaceae

Target:  

COX NF-κB

Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .
2
Esculentoside H
Esculentoside H
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2 Cited Publications
Cat. No.: HY-N2205
CAS No.: 66656-92-6
Category:  

Triterpenes Terpenoids Phytolacca acinosa Roxb. Plants Disease Research Fields Phytolaccaceae Cancer

Target:  

NF-κB JNK

Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta . Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease . Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression .
Precocene II
Precocene II
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Cat. No.: HY-122940
CAS No.: 644-06-4
Purity:  99.95%
Synonyms: Ageratochromene
Category:  

Natural Products Animals Other Diseases Disease Research Fields

Target:  

Endogenous Metabolite

Precocene II (Ageratochromene) is a plant larva hormone antagonists that inhibits the biosynthesis of juvenile hormone. Precocene II inhibits corpora allata function and downregulates juvenile hormone levels, while exerting multiple effects including inducing precocious metamorphosis, forming macropterous morphs, inhibiting ovarian growth, producing cytotoxicity, disrupting insect development, and causing sterility and kidney damage. Precocene II blocks normal nymphal development, causes renal tubular damage and increases blood urea nitrogen levels, and also blocks juvenile hormone biosynthesis in vitro. Precocene II undergoes oxidative metabolism catalyzed by NADPH-dependent monooxygenase to generate a variety of metabolites. Precocene II can be applied in studies related to insect growth regulation and nephrotoxicity .
Phytolacca americana Lectin
Phytolacca americana Lectin
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Cat. No.: HY-NP187
Synonyms: PWM
Phytolacca americana Lectin (PWM) is an acidic monomeric glycoprotein specific to N-acetylglucosamine and a B cell-specific stimulator. Phytolacca americana Lectin acts as a mitogen to induce cell mitosis. Phytolacca americana Lectin sensitizes B cells to Toll-like receptor stimulation, enabling their activation by immunostimulatory DNA. When used in combination with copurified microbial Toll-like receptor ligands, Phytolacca americana Lectin triggers B cell proliferation and immunoglobulin secretion .
Eleutherol
Eleutherol
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Cat. No.: HY-N7626
CAS No.: 480-00-2
Category:  

Infection Iridaceae Monophenols Eleutherine plicata Herb. Phenols Plants Disease Research Fields

Target:  

Fungal Glycosidase

Eleutherol is a naphthalene isolated from E. americana with antifungal activities . Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL . Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM .
Eleutherin
Eleutherin
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Cat. No.: HY-N8248
CAS No.: 478-36-4
Synonyms: (+)-Eleutherin
Category:  

Quinones Iridaceae Anthraquinones Eleutherine plicata Herb. Plants Disease Research Fields Cancer

Target:  

Topoisomerase

Eleutherin is a type of naphthoquinone derivative with the protective effect against the injury ofhuman umbilical vein endothelial cells (HUVECs), which can be isolated from the edible bulbs of Eleutherine americana (Hong-Cong) .
Aluminum potassium sulfate
Aluminum potassium sulfate
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Cat. No.: HY-W134301
CAS No.: 10043-67-1
Synonyms: Potassium alum
Target:  

Biochemical Assay Reagents

Research Areas:  

Infection

Aluminum potassium sulfate (Potassium alum) is an egg white adjuvant. Aluminum potassium sulfate acts as a mordant to help dyes bind to tissue components, enhancing the staining effect and stability during staining. Aluminum potassium sulfate can induce allergic reactions in mice. Aluminum potassium sulfate can be used in research for bacterial and tissue staining .
Chlorogenin
Chlorogenin
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Cat. No.: HY-N10451
CAS No.: 562-34-5
Category:  

Agave americana Linn. Agavaceae Plants Steroids

Target:  

Others

Chlorogenin is a natural product that can be isolated from the flowers of Agave americana .
Periplanetasin-4
Periplanetasin-4
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Cat. No.: HY-P11114
CAS No.: 2206807-06-7
Target:  

Bacterial p38 MAPK Reactive Oxygen Species (ROS) Apoptosis Caspase

Research Areas:  

Infection Inflammation/Immunology

Periplanetasin-4 is an antimicrobial peptide that can be derived from the American cockroach (Periplaneta americana). Periplanetasin-4 reduces cell rounding and apoptosis. Periplanetasin-4 blocks Clostridium difficile toxin A-induced ROS production and the activation of downstream p38 MAPK and p21. Periplanetasin-4 significantly increases mitochondrial calcium level, reduces DPH fluorescence intensity and vacuolar dysfunction in Candida albicans ATCC 90028 cells. Periplanetasin-4 significantly ameliorates toxin A-induced mucosal damage in the mouse gut. Periplanetasin-4 can be used for the study of colitis .
Mesuagin
Mesuagin
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Cat. No.: HY-N9650
CAS No.: 21721-08-4
Synonyms: Mammea A/AD cyclo D
Category:  

Flavonoids Mammea americana L. Plants Calophyllaceae Other Flavonoids

Target:  

Drug Derivative

Mesuagin (Mammea A/AD cyclo D) shows anticancer activity and can be isolated from the Mammea americana L. seeds .
Esculentoside B
Esculentoside B
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Cat. No.: HY-N6032
CAS No.: 60820-94-2
Synonyms: Phytolaccoside B
Category:  

Plants Phytolaccaceae Phytolacca americana L.

Target:  

Cholinesterase (ChE) JNK NF-κB Fungal

Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity .
Periplanetin
Periplanetin
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Cat. No.: HY-W415953
CAS No.: 21056-52-0
Category:  

Animals Saccharides Monosaccharides

Target:  

Sex Pheromone

Periplanetin is a peptide of the insect lipomotor hormone family (AKH family) that can be isolated from the secretion of the cervical organ of Periplaneta americana L. and Blatta orientalis L. The periplanetin peptide has potential analgesic activity and lowers the threshold of tonic seizures .
8-Desmethyleleutherin
8-Desmethyleleutherin
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Cat. No.: HY-N16339
CAS No.: 808148-30-3
Category:  

Quinones Iridaceae Eleutherine plicata Herb. Plants Naphthalene Quinones

Target:  

Bacterial

8-Desmethyleleutherin (Compound 2) is an antibacterial agent that can be extracted from the bulbs of Eleutherine americana. 8-Desmethyleleutherin has MIC values of both 62.5 µg/mL for S. aureus strains ATCC27664 and ATCC25923 .
Esculentoside A (Standard)
Esculentoside A (Standard)
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Cat. No.: HY-N0632R
CAS No.: 65497-07-6
Category:  

Triterpenes Terpenoids Phytolacca acinosa Roxb. Plants Phytolaccaceae

Target:  

Reference Standards COX NF-κB

Esculentoside A (Standard) is the analytical standard of Esculentoside A. This product is intended for research and analytical applications. Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .
Esculentoside C
Esculentoside C
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Cat. No.: HY-125121
CAS No.: 65931-92-2
Category:  

Triterpenes Terpenoids Phytolacca acinosa Roxb. Plants Phytolaccaceae

Target:  

Biochemical Assay Reagents

Esculentoside C is a triterpene saponin. Esculentoside C can be obtained from the root of Phytolacca esculenta .
Barpisoflavone A
Barpisoflavone A
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Cat. No.: HY-N2917
CAS No.: 101691-27-4
Category:  

Flavonoids Leguminosae Apios americana Medik. Plants Isoflavones

Target:  

Others

Barpisoflavone A is a natural product from Apios americana .
Esculentic acid
Esculentic acid
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Cat. No.: HY-N3866
CAS No.: 103974-74-9
Category:  

Triterpenes Labiatae Terpenoids Plants Vachellia nilotica (L.) P. J. H. Hurter & Mabb.

Target:  

COX

Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Esculentic acid is a pentacyclic triterpenoid that can be extracted from the Chinese herb Phytolacca esculenta .
SHP2-IN-29
SHP2-IN-29
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Cat. No.: HY-N12915
CAS No.: 2130080-86-1
Category:  

Microorganisms Monophenols Phenols

Target:  

SHP2 Phosphatase

SHP2-IN-29 (Compound 3) is a potent SHP2 inhibitor with an IC50 value of 0.18 μM. SHP2-IN-29 also has inhibitory activity against PTP1B and TCPTP, with IC50 values of 4.27 and 4.74 μM, respectively.
Esculentoside L
Esculentoside L
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Cat. No.: HY-N18168
CAS No.: 130364-33-9
Category:  

Terpenoids Plants Pentacyclic Triterpenoids Phytolaccaceae Phytolacca americana L.

Target:  

Others

Esculentoside L is a triterpene saponin present in the roots of Phytolacca americana. Esculentoside L increases the intracellular accumulation of calcein in multidrug-resistant human ovarian cancer cells. Esculentoside L exerts no significant cytotoxic activity against non-cancerous cells and hepatocytes. Esculentoside L can be used in studies related to multidrug-resistant human ovarian cancer .
Assay Types